Monitoring and robust adaptive control of fed-batch cultures of microorganisms exhibiting overflow metabolism [abstract]

Monitoring and robust adaptive control of fed-batch cultures of microorganisms exhibiting overflow metabolism [abstract]

Blog Article

Overflow metabolism characterizes cells strains that are likely to produce inhibiting by-products resulting from an excess of substrate feeding and a saturated respiratory capacity.The critical substrate level separating the two different metabolic pathways is generally not well defined.Monitoring Aplicación de métodos geoestadísticos en el modelado espacio-temporal de los niveles de agua subterránea del acuífero Valle de Sébaco, Nicaragua. of this kind of cultures, going from model identification to state estimation, is first discussed.Then, a review of control techniques which all aim at maximizing the cell productivity of fed-batch fermentations is presented.

Two main adaptive control strategies, one using an estimation of the critical substrate level as set-point and another regulating the by-product Redéfinition des récits urbains : analyse de deux déplacements du centre politique de Macapá (1944 et 1967) concentration, are proposed.Finally, experimental investigations of an adaptive RST control scheme using the observer polynomial for the regulation of the ethanol concentration in Saccharomyces cerevisiae fed-batch cultures ranging from laboratory to industrial scales, are also presented.